Darry J.Oswald's Articles in Flu-Immune System Show All|Display Category|Title|Newest|Oldest Effective Fever Treatment? A part of the brain called the hypothalamus acts as the body's thermostat. When all is well in the body, the hypothalamus is set at the normal body temperature. Fever develops when the hypothalamus is set to a higher-than-normal temperature. This resetting of the hypothalamus is usually caused by small molecules called pyrogens in the blood. Pyrogens can come from outside the body (external) or can be produced inside the body (internal). External pyrogens include toxins (p...

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